Processing of long-stored archival Papanicolaou-stained cytological smears

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Isolation of DNA from archival Papanicolaou stained cytological smears using a simple salting-out procedure.

DNA from archival Papanicolaou stained and unstained cytological smears was successfully isolated using a simple, rapid and inexpensive salting-out procedure. The quality of DNA was controlled by polymerase chain reaction (PCR) amplification of segments of the human beta-globin, human beta-actin and human papillomavirus L1 genes. Only negligible differences in amplification efficiency were obse...

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Cytological diagnosis of virus-infected cells in Papanicolaou smears and its application in clinical practice.

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ژورنال

عنوان ژورنال: British Journal of Cancer

سال: 1996

ISSN: 0007-0920,1532-1827

DOI: 10.1038/bjc.1996.576